Senolytic is from the words senescence and -lytic, “destroying”. Some NIH research indicates that senolytic substances can kill or weaken dormant PCa cells. Dormancy might be caused by radiation, ADT, or chemo, among others. Fisetin is one of the most powerful senolytics known. Curcumin, although not as potent, is also a powerful senolytic. The oral dose …
Category Archives: Uncategorized
Books
I don’t receive a dime. Just books that I found valuable out of the hundreds that I have read. Dr. Charles Myers: Beating Prostate Cancer (Hormonal Therapy & Diet, 1) (Hormonal Therapy & Diet, 1) by Dr. Charles Snuffy Myers (2007-05-03) Dr. Edward Friedman: The New Testosterone Treatment: How You and Your Doctor Can Fight …
My History
In 2015 my PSA went above 4 ng/ml, the magic number that indicates possible cancer. I put off a biopsy since I had heard on the internet that it was rife with side effects and pain. Lesson learned: lots of bro-science, individual experiences, and conspiracy theories on the internet. They are mostly just entertainment or …
Plan
My prostate cancer is Gleason 4+5, one local lymph node positive, seminal vessel and bladder neck invasion. I had radical prostatectomy surgery in 12/2018. At the time the doctors at the Mayo clinic told me that the cancer would return in 3 weeks to 3 months. My PSA would rise “guaranteed”. And I needed to …
PrC Supplements
Note that this post will be changing frequently. As I make new “discoveries” I incorporate and modify accordingly. And as new evidence emerges and a substance goes up in evidence ranking or down I either add it or decrease or adjust the dose. And when a substance moves into the “lineup” another one might be …
Vitamin D status
Vitamin D is a group of steroids involved in many biological effects including body absorption of calcium, magnesium, and phosphate.25-hydroxy vitamin D in the serum is measured to determine a person’s vitamin D status.All-mortality risk (cardiac risk, cancer risk, etc) increases considerably as serum vitamin D levels are lower.Prostate cancer specific mortality risk is similar …
Blood metrics
This is certainly not meant to be an all inclusive list of metrics. It is only a list of ones that I have found that I think might be of value. I only include units on a few of them. If you want specific details on one let me know and I’ll do my best …
Exercise
Exercise has been shown to have a preventative effect against PCa. And studies indicate that it has an even more dramatic effect on PCa death. From an NIH study of over 2,000 men: Men who exercised vigorously more than 3 hours per week of vigorous activity had a 61% lower risk of PCa death compared …
Hormonal manipulation
Hormonal manipulation is likely one of the primary ways to hold PCa in check. Short descriptions and list of abbreviations: ADT: Androgen Deprivation Therapy (reduction of androgens to very low levels: typically serum DHT and testosterone will be close to undetectable). AI: Aromatase Inhibitor. Some portion of testosterone is converted to estrogen via the aromatase …
Continuous Glucose Monitor (CGM)
Recently I purchased a freestyle libre CGM. I’ve had it for a few days now. What I have noticed is: Super convenient and nice to get your blood glucose charts all night/day. Can be linked to a PC so that data can be extracted. However, this is a somewhat cumbersome process. Still worthwhile if you …
Prostate Cancer Adventures 